Ginkgo Bioworks has introduced the launch of Ginkgo Enzyme Companies. Ginkgo Enzyme Companies is powered by extremely excessive throughput screening and machine learning-guided protein design, in addition to optimized proprietary bacterial and fungal host strains.
Ginkgo Enzyme Companies solves challenges for R&D groups growing enzymes, from discovery of novel enzyme exercise by way of optimization of enzyme perform and huge scale manufacturing.
Enzymes are precious biocatalysts used throughout a variety of industries together with within the manufacturing of medicines, meals, supplies, and past. Ginkgo Bioworks’ end-to-end Enzyme Companies assist R&D leaders seeking to determine new enzyme exercise to switch present chemical synthesis steps, enhance enzyme specificity, exercise, and stability in industrially related circumstances, and optimize the manufacturing of enzymes for lowered value of products and environmental influence.
Ginkgo Bioworks has supported enzyme R&D applications throughout a variety of industries, together with biopharma manufacturing and discovery. Notable enzyme companies tasks embody breakthrough work with Aldevron to enhance the manufacturing effectivity of vaccinia capping enzyme, a important reagent used within the manufacturing of mRNA vaccines, and a just lately introduced partnership with Merck to develop Biocatalysts for energetic pharmaceutical ingredient (API) manufacturing.
Ginkgo Bioworks’ suite of companies
Ginkgo’s suite of companies covers the complete end-to-end course of for enzyme R&D, offering synergies between enzyme sequence, host pressure, and manufacturing processes that may allow business success.
Ginkgo Enzyme Companies contains: novel enzyme discovery, enzyme perform and stability optimization, entry to optimized host strains for strong expression, optimized fermentation course of growth, and manufacturing scale-up, course of growth and tech switch.
“At Ginkgo, we’re always working to enhance our platform to offer best-in-class companies to allow our prospects to fulfill their R&D challenges head on. As a horizontal platform, we have now the pliability, breadth, and scale to serve prospects throughout biocatalysis, diagnostics, and past with the complete spectrum of instruments they should uncover, develop, and deploy enzymes for his or her processes and merchandise,” mentioned Behzad Mahdavi, SVP of biopharma manufacturing and life sciences instruments.
“With world class expression hosts, automation, computational design, and fermentation capabilities, we’re excited to associate with firms throughout all industries to carry their enzyme-dependent merchandise from conception to market extra swiftly and reliably than ever earlier than.”